Dynamical susceptibility contrast (DSC) and arterial spin labeling (ASL) are MRI techniques to quantify brain tissue perfusion. A voxel-wise analysis in 23 patients showed a moderate to strong linear relationship between tumoral cerebral blood flow measured by 2D echo planar imaging, pseudo-continuous ASL (pCASL) and leakage corrected, cerebral blood volume measurements by DSC. Additionally, mean and 90th percentile of tumor perfusion of all patients showed a strong linear relationship. In conclusion, 2D EPI pCASL is a viable alternative to DSC for perfusion measurements of brain tumors.
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