Abstract #3355

Pain and the NeuroMatrix in the Brain: Feasibility and Safety Study of 3T DWI in a Chronic Low Back Pain Patient Treated with Spinal Cord Stimulation

Isaiah Ailes¹, KiChang Kang¹, Anish Sathe¹, Jingya Miao¹, Leonard A. Frizon², Laura Krisa¹, Kristen Fleming¹, Peter Natale¹, Kiran Talekar¹, Devon Middleton¹, Feroze Mohamed¹, Ashwini Sharan¹, and Mahdi Alizadeh¹

¹Thomas Jefferson University, Philadelphia, PA, United States, ²Faculdades Pequeno Príncipe, Curitiba, Brazil

Synopsis

Spinal cord stimulation (SCS) in patients with failed back surgery syndrome aims to reduce neuropathic pain. However, minimal studies show a safe procedure using 3T diffusion weighted imaging (DWI) MRI for patients with SCS. Additionally, more studies looking at the neurological SCS treatment responses can lead to better optimization of SCS. It was our objective to safely develop a systematic procedure for 3T DWI MRI while also generating a map of the neural network connectivity in structures associated with pain. Long term application of this protocol aims to provide an objective assessment to SCS treatment.

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