Abstract #3367

Reproducibility of Chemical Shift-Encoded MRI Fat Quantification in Liver Across Field Strengths in Patients with Iron Overload

Zihan Wang^1,2, Scott B Reeder, MD, PhD^1,2,3,4,5, and Diego Hernando, PhD^2,3

¹Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁴Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁵Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

The purpose of this study is to assess the reproducibility of CSE-MRI methods to measure proton density fat fraction (PDFF) in liver in patients with iron overload. The PDFF measurements of 31 patients with known or suspected iron overload and 10 healthy volunteers were imaged at both 1.5T and 3.0T. Patients were separated into four groups with increasing liver iron concentration (LIC). The reproducibility across field strengths was quantified within each group and reported below.

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