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Abstract #3424

Free-breathing liver T1 mapping for quantitative oxygen consumption

Janaka Wansapura1
1Advanced Imaging Research Center, University of Texas Southwestern, Dallas, TX, United States


We introduce a dual flip angle T1 method based on respiratory triggered cine spoiled gradient echo acquisition. The method is used to assess the change in T1 of liver tissue between breathing medical air and 100% O2 in an animal model. Our results show small but significant decrease in T1 of liver due to hypoxia, indicating increased oxygen partial pressure in tissue.

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