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Abstract #3426

The relationship of arterial input function between abdominal aorta and hepatic artery

Jie Huang1, Yuancheng Liu2, Xianchun Zeng2, Chunqi Qian1, and Erik M. Shapiro1
1Michigan State University, East Lansing, MI, United States, 2Guizhou Provincial People's Hospital, Guiyang, China


The hepatic artery (HA) input is required in the dual-input, two-compartment model of studying liver function with dynamic gadoxetate-enhanced MRI. The dynamic contrast agent concentration in abdominal aorta (AA) is usually measured and used as the arterial input function instead of that measured in the HA because its small size. In this study, we determined the relationship between these two concentrations. We found that the measured arterial input function in AA can be reliably used as the HA input function with a suppression scaling factor taken into account.

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