Simultaneous Mapping of Water Diffusion Coefficients and Metabolite Distributions of the Brain Using MRSI without Water Suppression
Rong Guo1,2, Yudu Li1,2, Yibo Zhao1,2, Tianyao Wang3, Yao Li4, Brad Sutton1,2,5, and Zhi-Pei Liang1,2
1Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 3Radiology Department, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China, 4School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, 5Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States
The feasibility of high-resolution metabolic imaging using water-unsuppressed MRSI has been recently demonstrated in clinical settings using SPICE. This work utilizes the unsuppressed water spectroscopic signals for distortion-free mapping of water diffusion coefficients, thus adding a new feature to SPICE for multi-modal brain mapping. Experimental results demonstrated that simultaneous distortion-free diffusion imaging at 1.0×1.0×2.0 mm3 resolution and metabolic imaging at 2.0×3.0×3.0 mm3 nominal resolution were successfully obtained in a total 8-min scan.
This abstract and the presentation materials are available to members only;
a login is required.