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Abstract #3595

Measuring the stiffness of subcortical gray matter structures with virtual MR elastography in preterm and term infants

Miaomiao Wang1, Yao Ge1, Xianjun Li1, Congcong Liu1, and Jian Yang1
1the first affiliated hospital of Xi'an Jiaotong university, Xi'an, China

Synopsis

MR elastography is a promising approach for describing biomechanical properties. Some studies investigated stiffness of subcortical gray matter (SGM), which are critical for cognitive. However, they have not been explored in infants. MRE has some limitations in application of infants, and this study aims to measure SGM stiffness in preterm and term infants using virtual MRE. Our study suggested that virtual shear stiffness of SGM were similar between the preterm at term equivalent and the term, and GP is the stiffest region. This finding suggested that virtual MRE is a sensitive method to characterize the SMG maturity in infants.

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Keywords