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Abstract #3635

Postnatal age-related change of brain volume and its association with neurobehavior outcome in term neonates

Yuying Feng1, Linlin Zhu1, Peng xuan Bai1, Yao Ge1, Congcong Liu1, Na Zhang1, Yichu He2, Feng Shi2, Xiaocheng Wei3, Jian Yang1, and Chao Jin1
1The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China, 2Department of Research and Develpoment, Shanghai United Imaging Intelligence Co., Shanghai, China, 3Xiaocheng Wei, GEHealthcare, Beijing, China

Synopsis

Neonatal period is an important stage of brain development, exploring the development and evolution of brain region at this stage is significant for studying brain development and disease mechanisms. We analyzed the relationship between segmented brain region volume and postnatal age in term neonates, the results showed that, after controlling for gestational age, birth weight, body length, head circumference and gender factors, the volume of most brain regions of neonates was positively correlated with postnatal age. In addition, there is no correlation between the volume of most brain regions and neurobehavioral scores.

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Keywords