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Abstract #3639

Global and Regional Iron Content Changes of Gray Nucleus Using Quantitative Susceptibility Mapping in Type 2 Diabetes Mellitus Patients

Rui Hu1, Yangyingqiu Liu1, Bingbing Gao1, Wanyao Li1, Weiwei Wang1, Qingwei Song1, Ailian Liu1, and Yanwei Miao1
1Radiology, First Affiliated Hospital of Dalian Medical University, Dalian, China


Assessing whole-structural and regional high iron content in deep gray matter nuclei using STAGE-based QSM in T2DM Patients. Excessive deposition and uneven distribution of iron protein occur in all nuclei in T2DM patients. The MSVwh of significant differences (P < 0.05) between groups were present in right HCN, right PUT, bilateral GP, right STN and left GF, with the largest AUC of 0.723 in the right GP. The MSVhi in right HCN, right PUT, bilateral GP and left GF were significant differences (P < 0.05) With a largest AUC of 0.714 in right GP.

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