Pain management during labor is an essential part of general obstetric care. Use nonpharmacological methods such as transcutaneous electrical nerve stimulation (TENS) for pain relief is necessary because the risk from anesthetics and analgesics to the mother and fetus should always be considered. Therefore, we investigate the neural network alteration of the brain in pain relief by TENS during labor. Our findings indicated the TENS during labor might change functional connectivity of the pain-related network to reach the effect of pain relief, which improve our understanding of the neural representations of nociceptive and visceral pain-related networks.
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