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Abstract #3832

New parameters on CEST imaging by multi pool model in gliomas in comparison with conventional IVIM and 11C-MET uptake on PET/CT

Yasukage Takami1, Naruhide Kimura1, Katsuya Mitamura1, Takashi Norikane1, Keisuke Miyake2, Tatsuya Yamasaki3, Kazuo Ogawa3, Mitsuharu Miyoshi4, Atsushi Nozaki4, and Yoshihiro Nishiyama1
1Department of Radiology, Faculty of Medicine, Kagawa University, Miki-cho, Kita-gun, Japan, 2Department of Neurological Surgery, Faculty of Medicine, Kagawa University, Miki-cho, Kita-gun, Japan, 3Kagawa University Hospital, Miki-cho, Kita-gun, Japan, 4GE Healthcare, Hino-shi, Japan

Synopsis

The purpose of this study was to evaluate the correlation among parameters on CEST imaging by multi pool model, IVIM and 11C-methionine (MET) uptake on PET/CT in gliomas. The maximum values of the parameters on CEST imaging, the minimum parameters (ADC, D, D*) and maximum f on IVIM were measured respectively. 11C-MET uptake was semiquantitatively assessed using tumor-to-contralateral normal brain tissue (T/N) ratio. Several strong correlations were observed among some of the parameters. These preliminary results suggest that parameters on CEST imaging by multi pool model and IVIM seems to correlate with 11C-MET uptake on PET/CT in gliomas.

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