Direct quantification of cerebral metabolic rate of oxygen consumption (CMRO2) is possible with dynamic 17O-MRI after inhalation of isotope-enriched 17O2. In this work, we investigated oxygen metabolism in posterior fossa tissue including cerebellum, pons and midbrain. The determined CMRO2 values in these areas were in good agreement with literature values obtained by 15O-PET studies. Our results demonstrate that dynamic 17O-MRI may provide a valuable tool for direct measurement of CMRO2 in posterior fossa tissue.
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