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Abstract #3936

Correction of Bias in Single Reference Variable Flip Angle T1-mapping with Simple Extrapolation Method

Michael Malmberg1, Henrik L Odéen1, and DENNIS L PARKER1
1University of Utah, Salt Lake City, UT, United States

Synopsis

Single reference variable flip angle T1 mapping is subject to some remaining bias due to T2* effects between baseline and dynamic acquisitions. Previous work determined a computationally expensive correction for this bias. In this work, we present a much simpler extrapolation method to correct for T2* related bias in T1. This study provides an analysis through simulation of the benefits and drawbacks of this simpler extrapolation correction compared to the previous correction for bias on the SR-VFA T1 calculation.

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