We demonstrated that, our proposed T2 relaxometry-based free water mapping, CSFF, could be an imaging biomarker of dilated PVS and CSF clearance function by correlating it with multiple brain clearance-related measures including PVS score, PC-MRI based aqueduct CSF flow, dynamic PET based ventricle CSF clearance, amyloid beta and tau deposits. Our results show that CSFF is positively associated with PVS score, aging, amyloid beta and tau deposits. And it negatively correlates with net aqueduct CSF flow, ventricle CSF flow, and cognitive score.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords