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Abstract #4042

MR Elastography: Clinical Protocol Optimization for Liver Stiffness Estimation

Manjunathan Nanjappa1, Brian Raterman1, Bradley D. Bolster, Jr2, Kannengiesser Stephan3, Ning Jin2, and Arunark Kolipaka1
1Department of Radiology, The Ohio State University, Columbus, OH, United States, 2MR Collaborations, Siemens Medical Solutions USA, Malvern, PA, United States, 3Siemens Healthineers, Erlangen, Germany


Magnetic resonance elastography (MRE) has become a standard clinical tool to stage liver fibrosis and it is important to optimize the imaging protocols to achieve robust stiffness measurement. Imaging was performed using a 3T MRI scanner on 20 healthy adult volunteers with varied driver powers and acquisition parameters. The stiffness value at 60Hz across the settings was found to be stable for all the subjects. 40-50% driver power with 20-35mT motion encoding gradient amplitude would deliver adequate shear waves to achieve diagnostic quality of liver stiffness maps.

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