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Abstract #4179

Deep learning for term neonate hypoxic ischemic encephalopathy diagnosis on structural brain MR images: a retrospective study

Tongjia Gan1, Wenzhen Zhu1, Jingjing Shi1, and Wenzhi Lv2
1Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2Department of Artificial Intelligence, Julei Technology Company, Wuhan, China

Synopsis

This study aims to diagnose objectively term neonate hypoxic ischemic encephalopathy (HIE) by using deep learning network to extract deep information from multiple modalities of conventional magnetic resonance (MR) images. Neonate HIE diagnosis accuracy is restricted to lesion diversity, MR images quality, high interobserver variability. The network got high diagnosis accuracy in the ROC curve. The network could detect severe neonate HIE with characteristic appearance such as basal ganglia injury and periventricular leukomalacia. The network can help diagnosis neonate HIE objectively without the effect of different radiologist experience and contribute to risk stratification and clinical decision making.

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