Abstract #4181

Evaluation of Secondary Prevention Effectiveness of Ginkgo Biloba Extract (EGb 761) in Acute Ischemic Stroke by QSM and Venous Oxygen Saturation

Wen-Ting Lan¹, Yue-Fei Wu², Hui Zhang¹, Xin-Zhong Ruan¹, Yi Huang³, Xiao-Jing Li⁴, and Yunzhu Wu⁵

¹Department of Radiology, Ningbo First Hospital, Ningbo Hospital of Zhejiang University, Ningbo, China, ²Department of Neurology, Ningbo First Hospital, Ningbo, China, ³Department of Neurosurgery, Ningbo First Hospital, Ningbo, China, ⁴Department of Gerontology, Ningbo First Hospital, Ningbo, China, ⁵MR Scientific Marketing, SIEMENS Healthineers, Shanghai, China

Synopsis

In this study, we applied quantitative susceptibility mapping (QSM) and venous oxygen saturation measurement in acute ischemic stroke patients who took ginkgo biloba extract (EGb 761) treatment. EGb 761’s secondary prevention effectiveness of ischemic stroke patients with cerebral microbleeds was similar to Aspirin. Furthermore, Ginkgo biloba extract could not only improve neuroprotective efficiency and prognosis by increasing oxygen saturation of the vein near infarction, but also could reduce the incidence of adverse side effects such as gastrointestinal ulcers and bleeding usually caused by Aspirin.

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