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Abstract #4192

A comparative study of multi-parameters from Gd-EOB-DTPA-enhanced MRI in the assessment of liver function in patients with cirrhosis.

Yexin He1, Jia Shao1, Jinxia Guo2, Qiang Gao1, and Cheng Xu1
1SHANXI PROVINCIAL PEOPLE'S HOSPITAL, Taiyuan, China, 2GE Healthcare, Beijing, China


Gd-EOB-DTPA-enhanced MRI was used to quantitatively assess liver function benefiting the follow-up of patients with chronic liver disease and the appropriate plan for liver cancer treatment. A systematic multi-parametric analysis with non-enhanced and Gd-EOB-DTPA-enhanced T1 weighted and T1 mapping MRI were conducted to assess the liver function in patients with cirrhosis. Independent factor for differentiation of A+N(normal and Child-Pugh A) and B+C (Child-Pugh B and C) were found to be RE_Liver, T1_Native, T1_Post and ΔT1_Liver, while for differentiation of Child-Pugh B and C were found to be ΔT1_Liver and SIR_Bdult/Muscle. Both combined model with these factors obtained better diagnostic performance.

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