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Abstract #4363

Development of measurement method of metabolite concentration in 1H MRS under B1 inhomogeneity at high magnetic field

Hidehiro Watanabe1
1Health and environmental risk division, National Institute for Environmental Studies, Tsukuba, Japan


The method for measurement of metabolite concentrations in 1H MRS in a human brain at high B0 field was proposed. A water phantom as a reference and a human brain area measured separately. The ratio of the reception sensitivities between uniform areas in the phantom and in the human brain can be computed from measured B1+s. The ratio between the VOI and the uniform area in the human brain can be computed by our previously reported ratio map method. Then, metabolite concentrations in the VOI can be calculated. Our method was demonstrated in the phantom experiments using metabolite mixtures.

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