Glucose concentrations at posterior cingulate cortex in 20 young healthy subjects were quantitated via detecting H1-α-glucose peak at 5.23 ppm in 1H MRS at 7T. The spectra were analyzed using LCModel with data excluding a range of the residual water peak using PPMGAP parameter, which simply corrected baselines around the H1-α-glucose peak distorted from the tail of the residual water peak. The mean glucose concentration was estimated to be 1.0 mM via both sequences. Cramer-Rao lower bounds of fitting H1-α-glucose peak were significantly smaller in the semi-LASER (mean: 33.1 %) than those in the short-TE STEAM (49.8 %).
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