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Abstract #4408

Comprehensive 3D quantitative transient response MRI

Gyula Kotek1, Willem van Valenberg1, Laura Nunez-Gonzalez1, Dirk H. J. Poot1, Mika W. Vogel2, and Juan A. Hernandez-Tamames1
1Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands, 2GE Healthcare, Hoevelaken, Netherlands

Synopsis

Unlike multi-parametric methods as MR Fingerprinting and quantitative transient imaging we present a quantitative MRI method based on the transient response without variation of experimental parameters (FA…). Our method is based on the exact solution of the recursive equation for the magnetization along an acquisition train. Based on this analytical approach we determine the requirements for the features and parameters of a repeated acquisition block to allow simultaneous estimation of experimental (B0, B1) and intrinsic (PD, T1, T2) parameters. The feasibility of the technique on clinical scanners is demonstrated by acquiring a comprehensive set of 3D in vivo parametric maps.

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