Magnetization transfer (MT) effect has been analyzed by the MT ratio (MTR) or quantitative MT (qMT). However, because the MTR lacks sensitivity and specificity to MT effect and qMT needs a long scan time, their application into clinical scenarios has been limited. In this paper, we introduce the dopMTR, a new MT data analysis and acquisition method that uses double saturation pulse offsets and powers. Simulations and experiments show that the dopMTR can provide more specific and sensitive quantification of the MT effect than the conventional MTR, with relatively brief acquisition times and easy data processing.
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