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Abstract #4426

Correlation of the 23Na Triple-Quantum Signal with Protein Size

Simon Reichert1, Dennis Kleimaier1, and Lothar Schad1
1Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany


This study demonstrates a correlation of protein size with sodium triple-quantum (TQ) signal. The TQ/SQ ratio of several globular proteins increased with protein size. Furthermore, strong sodium binding had a substantial impact on the TQ signal. The small protein α-Lactalbumin yielded a strong TQ signal due to strong sodium binding to a calcium binding site using a calcium-depleted protein.

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