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Abstract #4538

Visible "Butterfly" of the Cervical Spinal Cord: A Pilot Study Using 3D and 2D m-FFE with Inhomogeneous Magnetization Transfer Pulse

Takafumi Yoda1, Hajime Yokota2, Takayuki Sada1, Ryuna Kurosawa1, Koji Matsumoto1, Takashi Namiki3, Masami Yoneyama3, Guillaume Gilbert4, Yoshitada Masuda1, and Takashi Uno2
1Department of Radiology, Chiba University Hospital, Chiba, Japan, 2Department of Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan, 3Philips Japan, Tokyo, Japan, 4Philips Canada, Mississauga, ON, Canada


The purpose of this study is to find the parameters that provide the optimal trade-off in Signal-to-noise-ratio (SNR) and contrast-to-noise ratio (CNR) for 3D ihMT m-FFE (3D-ihMT) and to explore the feasibility of that for the segmentability of gray and white matters in the cervical spinal cord compared with 2D ihMT m-FFE (2D-ihMT). We recommend a Flip angle of 7 and TFE factor of 5 as an optimal trade-off between segmentability and artifact level, at least 16 nr repetitions are required for robust segmentation. The segmentability of 3D-ihMT could be increased to a level close to that of 2D-ihMT.

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