Abstract #4598

Quantitative analysis of Symptomatic and Asymptomatic Atherosclerotic Middle Cerebral Artery Plaques Using 7T Magnetic Resonance Imaging

Xiaoyan Bai¹, Qingle Kong², Zhiye Li¹, Pingping Fan¹, and Binbin Sui³

¹Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing Neurosurgical Institute, Beijing, China, Beijing, China, ²MR Collaboration, Siemens Healthineers Ltd., Beijing, China, Beijing, China, ³Tiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, Beijing, China, Beijing, China

Synopsis

A total of 40 MCA atherosclerotic plaques of 34 patients (20 symptomatic and 20 asymptomatic plaques) were quantitatively analyzed of plaque features including plaque burden, length, remodeling index, plaque distribution, and surface morphology using 7T vessel wall Magnetic Resonance Imaging (VW-MRI). Compared with the asymptomatic plaques, symptomatic MCA plaques had larger plaque length and higher plaque burden. Superior-wall distribution and irregular plaque surface were observed more commonly on the symptomatic MCA plaques. 7T VW-MRI is a promising method to evaluate the atherosclerotic plaque features at MCAs.

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