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Abstract #4598

Quantitative analysis of Symptomatic and Asymptomatic Atherosclerotic Middle Cerebral Artery Plaques Using 7T Magnetic Resonance Imaging

Xiaoyan Bai1, Qingle Kong2, Zhiye Li1, Pingping Fan1, and Binbin Sui3
1Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing Neurosurgical Institute, Beijing, China, Beijing, China, 2MR Collaboration, Siemens Healthineers Ltd., Beijing, China, Beijing, China, 3Tiantan Neuroimaging Center of Excellence, China National Clinical Research Center for Neurological Diseases, Beijing, China, Beijing, China


A total of 40 MCA atherosclerotic plaques of 34 patients (20 symptomatic and 20 asymptomatic plaques) were quantitatively analyzed of plaque features including plaque burden, length, remodeling index, plaque distribution, and surface morphology using 7T vessel wall Magnetic Resonance Imaging (VW-MRI). Compared with the asymptomatic plaques, symptomatic MCA plaques had larger plaque length and higher plaque burden. Superior-wall distribution and irregular plaque surface were observed more commonly on the symptomatic MCA plaques. 7T VW-MRI is a promising method to evaluate the atherosclerotic plaque features at MCAs.

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