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Abstract #4672

High Temporal and Spatial Pulmonary Dynamic Ventilation Imaging Using Hyperpolarized 129Xe MRI 

Hongchuang Li1, Haidong Li1, Ming Zhang1, Xiaoling Liu1, Xiuchao Zhao1, Yeqing Han1, Xianping Sun1, Chaohui Ye1, and Xin Zhou1
1Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences- Wuhan National Laboratory for Optoelectronics, Wuhan, China


The mutual restriction of temporal resolution and spatial resolution is a challenge for hyperpolarized gas dynamic MRI. Herein, we proposed a method to enhance the temporal resolution of pulmonary dynamic ventilation imaging without spatial resolution loss using hyperpolarized 129Xe MRI. Furthermore, compressed sensing undersampling technique was used to accelerate the MRI data acquisition.

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