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Abstract #4745

Distortion-Free DWI using PSF-EPI at High-Performance 0.5T MRI

Simin Liu1, Yunhao Xie2, Hai Luo2, Yishi Wang1, Sisi Li1, Jieying Zhang1, Ziyi Pan1, Ziyue Wu2, and Hua Guo1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Marvel Stone Healthcare Co., Ltd., Wuxi, China


Low-field MR systems with state-of-the-art hardware may improve the accessibility of MRI. DWI is valuable for diagnosing diseases, while it requires multiple averages at low-field MRI considering SNR. Given similar acquisition time, multi-shot EPI DWI can be considered alternatively. Particularly, the tilted-CAIPI accelerated multi-shot PSF-EPI has been proposed in recent years to achieve fast distortion-free DWI. This study tested the feasibility of PSF-EPI on a high-performance 0.5T MR scanner, and proposed a method for further noise reduction using B0 field information. The results show that PSF-EPI eliminates distortions and improves structure fidelity at tissue boundaries compared with interleaved EPI.

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