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Abstract #4746

Exploiting slice-by-slice B1 adjusted adiabatic refocusing RF pulses to improve diffusion weighted imaging at 7T

Yasmin Blunck1,2, Daniel Staeb3, Rebecca Glarin1, Leigh Johnston1,2, Jin Jin4, and Kieran O'Brien4
1Melbourne Brain Centre Imaging Unit, The University of Melbourne, Melbourne, Australia, 2Department of Biomedical Engineering, The University of Melbourne, Melbourne, Australia, 3Siemens Healthcare Pty Ltd, Melbourne, Australia, 4Siemens Healthcare Pty Ltd, Brisbane, Australia


The application of diffusion weighted imaging (DWI) at ultra-high field is hampered by severe B1 inhomogeneities leading to signal dropouts in certain parts of the brain. Utilising TR-FOCI pulses in a twice-refocussed spin echo DWI sequence can effectively recover signal in these areas, albeit at the cost of increased SAR. Maintaining this enhanced B1 homogeneity, this work demonstrates a ~30% reduction in SAR based on a slice-by-slice RF amplitude optimization.

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