Abstract #4746

Exploiting slice-by-slice B1 adjusted adiabatic refocusing RF pulses to improve diffusion weighted imaging at 7T

Yasmin Blunck^1,2, Daniel Staeb³, Rebecca Glarin¹, Leigh Johnston^1,2, Jin Jin⁴, and Kieran O'Brien⁴

¹Melbourne Brain Centre Imaging Unit, The University of Melbourne, Melbourne, Australia, ²Department of Biomedical Engineering, The University of Melbourne, Melbourne, Australia, ³Siemens Healthcare Pty Ltd, Melbourne, Australia, ⁴Siemens Healthcare Pty Ltd, Brisbane, Australia

Synopsis

The application of diffusion weighted imaging (DWI) at ultra-high field is hampered by severe B1 inhomogeneities leading to signal dropouts in certain parts of the brain. Utilising TR-FOCI pulses in a twice-refocussed spin echo DWI sequence can effectively recover signal in these areas, albeit at the cost of increased SAR. Maintaining this enhanced B1 homogeneity, this work demonstrates a ~30% reduction in SAR based on a slice-by-slice RF amplitude optimization.

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