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Abstract #4748

Characteristics of three factors that influence the diffusion signal with PGSTE and OGSE

Hinako Oshiro1,2, Junichi Hata1,2,3,4, Daisuke Nakashima3, Yawara Haga1,2, Naoya Hayashi1,2, Daisuke Yoshimaru2,3,4, Kei Hagiya2, and Hideyuki Okano2,3
1Tokyo Metropolitan University, Tokyo, Japan, 2RIKEN Center for Brain Science, Saitama, Japan, 3Keio University School of Medicine, Tokyo, Japan, 4The Jikei University School of Medicine, Tokyo, Japan


We investigated the characteristics of diffusion quantification values in a restricted structure with a capillary phantom in PGSTE and OGSE. Smaller structure sizes require shorter diffusion times for structure estimation. In OGSE, we observed a transition of diffusion coefficients under 10 ms for capillary sizes from 6-12 μm, but no differences for those from 25-100 μm. Moreover, it was necessary to consider the temperature dependence of the diffusion measurement at low temperatures. We developed a system to measure the effects on diffusion quantification values at three phases of different temperatures, structure sizes, and diffusion times.

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