Abstract #4762

Functional and structural connectomes of the lateral and medial geniculate nuclei in living humans using 7 Tesla MRI

Kavita Singh¹, Maria Guadalupe Garcia Gomar^1,2, Simone Cauzzo^1,3,4, and Marta Bianciardi^1,5

¹Brainstem Imaging Laboratory, Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Boston, MA, United States, ²National Autonomous University of Mexico, Mexico, Mexico, ³Sant'Anna School of Advanced Studies, Institute of Life Sciences, Pisa, Italy, ⁴Research Center E. Piaggio, University of Pisa, Pisa, Italy, ⁵Division of Sleep Medicine, Harvard University, Division of Sleep Medicine, Boston, MA, United States

Synopsis

The connectivity of lateral and medial geniculate nuclei with cortical and sub-cortical areas involved in visual and auditory functions is known in humans, yet their recently postulated connectivity with neuromodulatory, visceral and sensory brainstem nuclei is understudied. This is due to limited resolution of clinical scanners and lack of brainstem atlas in living humans. To this end, we applied our recently developed in-vivo atlas of brainstem and diencephalic nuclei to 7 Tesla HARDI and resting-state fMRI, and mapped structural and functional connectomes of lateral and medial geniculate nuclei with brainstem nuclei along with cortical and sub-cortical regions.

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