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Abstract #4762

Functional and structural connectomes of the lateral and medial geniculate nuclei in living humans using 7 Tesla MRI

Kavita Singh1, Maria Guadalupe Garcia Gomar1,2, Simone Cauzzo1,3,4, and Marta Bianciardi1,5
1Brainstem Imaging Laboratory, Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Boston, MA, United States, 2National Autonomous University of Mexico, Mexico, Mexico, 3Sant'Anna School of Advanced Studies, Institute of Life Sciences, Pisa, Italy, 4Research Center E. Piaggio, University of Pisa, Pisa, Italy, 5Division of Sleep Medicine, Harvard University, Division of Sleep Medicine, Boston, MA, United States


The connectivity of lateral and medial geniculate nuclei with cortical and sub-cortical areas involved in visual and auditory functions is known in humans, yet their recently postulated connectivity with neuromodulatory, visceral and sensory brainstem nuclei is understudied. This is due to limited resolution of clinical scanners and lack of brainstem atlas in living humans. To this end, we applied our recently developed in-vivo atlas of brainstem and diencephalic nuclei to 7 Tesla HARDI and resting-state fMRI, and mapped structural and functional connectomes of lateral and medial geniculate nuclei with brainstem nuclei along with cortical and sub-cortical regions.

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