Systemic Lupus Erythematosus (SLE) is a chronic, inflammatory, multisystem disease predominantly affecting young women. Patients with SLE have a significantly worse health-related quality of life compared to healthy subjects or patients with other chronic diseases. MSK manifestations in SLE patients are common, including reductions in bone quality. Studies using magnetic magnetic resonance spectroscopy (MRS) have shown that change in bone marrow fat amount and composition is associated with decreased bone quality. The aim of our study was to use MRS to assess differences of BMAT in SLE without treatment (n=28), SLE treated (n=15) and controls (n=21).
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