Abstract #5038
Validation of motion-robust, blood-suppressed, reduced-distortion liver diffusion techniques in a pulsatile motion phantom
Ruiqi Geng1,2, James Rice1,3, Yuxin Zhang1,2, David R. Rutkowski1,3, Alejandro Roldán-Alzate1,3, Arnaud Guidon4, and Diego Hernando1,2,5,6
1Radiology, University of Wisconsin-Madison, Madison, WI, United States, 2Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 3Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 4GE Healthcare, Boston, MA, United States, 5Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI, United States, 6Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States
Synopsis
Conventional liver diffusion MRI acquisitions suffer from several challenges including pulsatile motion-induced signal voids and B0-induced distortions. In this study, we validated motion-robust, blood-suppressed, reduced-distortion liver diffusion techniques in an anatomically accurate liver phantom including controlled pulsatile motion. By combining optimized motion-compensated, blood-suppressed diffusion waveforms (i.e. MODI) with msEPI acquisitions, superior image quality and quantitative performance can be achieved in the presence of various degrees of compressive tissue motion.
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