Meeting Banner
Abstract #0256

CHEAP and SLOW: a comprehensive acquisition protocol for downfield, upfield, and spectral editing 1H-MRSI at 7T

Guodong Weng1,2, Piotr Radojewski1,2, and Johannes Slotboom1,2
1Institute for Diagnostic and Interventional Neuroradiology, Support Center for Advanced Neuroimaging (SCAN), University of Bern, Bern, Switzerland, 2Translational Imaging Center, sitem-insel, Bern, Switzerland, Bern, Switzerland

Synopsis

Keywords: Spectroscopy, High-Field MRI, downfield, Spectral editing, MRSI

Motivation: Integration of downfield, upfield, and spectral editing MRSI in clinical studies

Goal(s): Generate high resolution downfield (0.37 ml) and upfield (0.2 ml) in vivo MRSI at 7T

Approach: CHEAP-ESPI and SLOW-EPSI were used for downfield and upfield (spectral editing) MRSI, respectively, in two healthy volunteers and one glioma patient.

Results: A 4-minute acquisition with CHEAP-EPSI suffices for downfield MRSI (ATP/GSH+ and NAA+), while a 9-minute acquisition with SLOW-EPSI is adequate for upfield (NAA) and spectral editing (2HG, GABA, and Glx) MRSI.

Impact: The combination of CHEAP-EPSI and SLOW-EPSI enables the measurement of downfield, upfield, and edited 3D MRSI within approximately 13 minutes, making it readily integrable into clinical routine examinations or scientific studies.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords

downfieldsubjectcheapupfieldbrainspectraleditingslow