Keywords: Quantitative Imaging, Low-Field MRI, liver
Motivation: Evaluation of patients with fatty liver disease can benefit from low-field scanners due to their larger bore size and reduced cost. However, fat is a cofounding factor for liver T1 mapping, and there is currently no reliable water-only T1 mapping method for low B0 field strengths.
Goal(s): To develop a practical water-only liver T1 mapping method at 0.55T.
Approach: Inversion recovery preparation combined with a 3-echo bSSFP spiral out-in-out-in (OIOI) readout was used to obtain water/fat separated images and quantify water-only T1.
Results: The proposed water-only T1 mapping method is insensitive to liver PDFF, compared to Cartesian MOLLI and water-fat in-phase T1 values.
Impact: For patients with fatty liver disease, this new method provides reliable water-only T1 mapping at low field strength (0.55T). This method may be incorporated into clinical protocols as an indicator of liver inflammation, fibrosis, and stiffness.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords