Abstract #0284

Initial demonstration of free-running whole-heart radial 4D flow using ultra-short echo times (UTE)

Efena Akporeha¹, Robin Ferincz¹, Tobias Rutz², Giulia M.C. Rossi¹, Mariana B.L. Falcao¹, Isabel Montón Quesada¹, Jérôme Yerly¹, Ruud B. van Heeswijk¹, Milan Prsa³, Michael Markl^4,5, Matthias Stuber^1,6, and Christopher W Roy¹

¹Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ²Service of Cardiology, Heart and Vessel Department, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ³Division of Pediatric Cardiology, Woman-Mother-Child Department, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ⁴Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ⁵Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States, ⁶Center for Biomedical Imaging (CIBM), Lausanne, Switzerland

Synopsis

Keywords: Flow, Heart, Whole-heart, UTE, Congenital Heart Disease

Motivation: Free-running phase-contrast whole-heart MRI, despite its ease of use and efficiency may suffer from artifacts and inaccuracy in the presence of non-laminar flow and high velocities due to prolonged echo times.

Goal(s): Our goal was to reduce the echo time in free-running radial 4D flow (radial 4D flow).

Approach: We incorporated ultra-short echo time (UTE) imaging techniques into our radial 4D flow framework.

Results: Net flow and peak flow measurements that correlate well with reference values were obtained in a cohort of healthy volunteers with the modified sequence and enabled qualitative evaluation of turbulent flow in patients with congenital heart disease.

Impact: The combination of UTE and radial 4D flow MRI marks a step towards a more precise and robust quantification of hemodynamics under complex conditions, in an effort to improve both diagnosis and patient outcomes.

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