Abstract #0285

Free-running 5D whole-heart MRI using a Gadolinium enhanced Fast-Interrupted Steady-State sequence to evaluate congenital heart disease

Christopher W Roy¹, Tobias Rutz², Milan Prša³, Ludovica Romanin^1,4, Jerome Yerly^1,5, Juerg Schwitter^2,6, Jessica AM Bastiaansen^7,8, and Matthias Stuber^1,5

¹Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ²Service of Cardiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ³Division of Pediatric Cardiology, Mother-Woman-Child Department, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ⁴Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, ⁵Center for Bio-medical Imaging (CIBM), Lausanne, Switzerland, ⁶Cardiac MR Center, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ⁷Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, ⁸Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland

Synopsis

Keywords: Myocardium, Cardiovascular, Congenital heart disease, Free-running, whole-heart

Motivation: There is a need for simplified and time-efficient dynamic whole-heart imaging in the evaluation of congenital heart disease patients.

Goal(s): To demonstrate the feasibility of Gadolinium enhanced 5D FISS CMR and compare it to established 2D and 3D CMR methods in a cohort of congenital heart disease patients.

Approach: Ejection fraction and vessel sharpness measurements derived from established 2D and 3D CMR are quantitatively compared to those obtained from the proposed 5D sequence.

Results: 5D FISS CMR is feasible for the evaluation of cardiac function and anatomy building towards an easy-to-use and time-efficient method for evaluating congenital heart disease.

Impact: Free-running 5D whole-heart MRI using a Gadolinium enhanced FISS sequence enables both measurements of cardiac function and evaluation of morphology in patients with congenital heart disease with a fixed six-minute scan time.

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