Keywords: Functional Connectivity, Brain Connectivity, brain stimulation
Motivation: TMS has become an invaluable asset in both research and clinical environments. However, variability in individual responses to TMS is a persistent issue, which limits its broader adoption.
Goal(s): The integration of TMS with fMRI through interleaved paradigms is a promising strategy for gaining insights into the factors that underlie this response variability.
Approach: Adopting an interleaved TMS-fMRI approach we explored the different factors of stimulation dose, sex differences, and cognitive state.
Results: Interleaved TMS-fMRI revealed individual dose-response patterns. Inherent sex differences were found between men and women. Precise timing of TMS relative to cognitive state demonstrated differential effects on relevant brain regions.
Impact: The findings represent a critical step toward addressing the challenge of response variability. TMS-fMRI promises to be a valuable tool for not only understanding factors that influence TMS response but also for potentially enhancing response rates in TMS applications.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords