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Abstract #0341

Joint sequence optimization beats pure neural network approaches for super-resolution TSE

Hoai Nam Dang1, Vladimir Golkov2,3, Jonathan Endres1, Simon Weinmüller1, Felix Glang4, Thomas Wimmer2, Daniel Cremers2,3, Arnd Dörfler1, Andreas Maier5, and Moritz Zaiss1,4,6
1Institute of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany, 2Technical University of Munich, Munich, Germany, 3Munich Center for Machine Learning, Munich, Germany, 4Magnetic Resonance Center, Max-Planck-Institute for Biological Cybernetics, Tuebingen, Germany, 5Department of Computer Science, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Erlangen, Germany, 6Department Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany

Synopsis

Keywords: AI/ML Image Reconstruction, Machine Learning/Artificial Intelligence, super-resolution, turbo-spin-echo, joint-optimization

Motivation: TSE flip angle trains can have a strong influence on the actual resolution of the acquired image and have consequently a considerable impact on the performance of a super-resolution task.

Goal(s): We demonstrate the advantage of end-to-end optimization of sequence and neural network parameter compared to pure network training approaches.

Approach: This MR-physics-informed training procedure jointly optimizes radiofrequency pulse trains of a PD- and T2-weighted TSE and subsequently applied CNN to predict corresponding PDw and T2w super-resolution TSE images.

Results: The method generalizes from simulation-based optimization to in vivo measurements and acquired super-resolution images show higher accuracy compared to pure network training approaches.

Impact: Acquired super-resolution image may improve evaluation of the data. Reduction of acquisition time compared to direct high-resolution acquisition leads to increase in patient comfort and minimization of motion artifacts.

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Keywords