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Abstract #0583

Improving Reproducibility in Quantitative 4D Flow MRI Using AI-Driven Fully-Automated Processing and Analysis

Ethan Johnson1, Kai Yang1, Elizabeth Weiss1, Kelly Jarvis1, Haben Berhane1, Aparna Sodhi2, Cynthia K Rigsby2, and Michael Markl1
1Northwestern University, Chicago, IL, United States, 2Ann & Robert H. Lurie Children’s Hospital, Chicago, IL, United States

Synopsis

Keywords: Quantitative Imaging, Quantitative Imaging, 4D flow MRI, hemodynamics

Motivation: Reproducibility is fundamentally an issue for quantitative MRI, and any human intervention required for processing can be a significant source of variability.

Goal(s): This study aims to improve reproducibility in quantitative 4D flow MRI by removing all human input from processing, using AI-driven tools.

Approach: Hemodynamic parameters quantified by a fully automated neural-network-based processing tool for 4D flow MRI were compared to quantifications performed by two sets of human observers.

Results: Moderate but appreciable limits of agreement were observed between quantifications performed by different human observers. Quantified values from fully-automated processing were comparable to those from humans, but all inter-observer variability was eliminated.

Impact: This study offers a stable baseline for improving measurement reliability in quantitative 4D flow MRI by removing all manual human inputs required.

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Keywords