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Abstract #0608

3D Image Enhancement for High-Resolution ky-kz Accelerated 3D LGE CMR

Omer Burak Demirel1, Manuel A Morales1, Jordan A Street1, Warren J Manning1,2, and Reza Nezafat1
1Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States, 2Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: Prolonged scan times in high-resolution 3D late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging hinders the full potential in clinical applications.

Goal(s): The primary goal of this study was to develop and evaluate a 3D enhanced-resolution for 2D (ky-kz) accelerated 3D LGE imaging.

Approach: A 3D generative adversarial network was implemented to enhance the spatial resolution of 2D-accelerated 3D LGE images.

Results: The proposed method at 6-fold acceleration (3-fold in ky and 2-fold in kz) maintained intricate scar details and improved image quality.

Impact: The improvement in acquisition speed by 2D acceleration may benefit patients presenting with heavy respiratory motion and may be less sensitive to contrast washout.

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Abstract

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