Keywords: Prenatal, Prenatal
Motivation: Understanding placental dysfunction's role in small-for-gestational-age (SGA) fetal neurodevelopment is crucial; this study seeks to fill that gap, enhancing prenatal care.
Goal(s): The primary goal is to assess whether MRI can effectively quantify the relationship between placental function and fetal brain development in SGA pregnancies.
Approach: The study used IVIM, and T2* mapping to evaluate placental and fetal brain development, applying Pearson correlation and t tests for comparative analysis.
Results: Significant differences in placental perfusion and cortical properties between control and SGA groups were reported, demonstrating the feasibility of using MRI for in-utero assessment.
Impact: This study’s MRI approach could change prenatal care, allowing earlier detection of small-for-gestational age–related brain development issues, prompting interventions, and guiding research into neurodevelopmental support for affected neonates, with potential long-term cognitive benefits.
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