Keywords: Liver, Liver, T1 mapping, hepatic steatosis
Motivation: In evaluating T1 values in patients with hepatic steatosis, it is necessary to investigate the effect of fat because MOLLI is sensitive to fat.
Goal(s): To elucidate the clinical importance of MOLLI T1 mapping of the liver using TE=1.8 (AIOP) sequence in daily practice.
Approach: In 122 patients with suspected liver diseases, MOLLI T1 mapping with TE=1.8 (AIOP) was compared with that with TE=1.3 (OP) and TE=2.4 (IP).
Results: The positive correlation with high correlation coefficient between T1 value of the liver in AIOP sequence and FIB-4 score was observed in patients with hepatic steatosis (PDFF ≥10%).
Impact: T1 mapping using AIOP sequence will be critical for assessing liver fibrosis in patients with hepatic steatosis since T1 mapping obtained by OP and IP sequences have risk of over- and under-estimation of T1 measurements.
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