Keywords: CEST / APT / NOE, CEST & MT
Motivation: CEST-MRI typically requires a long scan time and an additional B0 map scan for inhomogeneity correction.
Goal(s): To implement a rosette readout for fast CEST imaging with improved robustness to bulk-motion and inherent correction of B0 inhomogeneity.
Approach: Rosette trajectories which sample more densely near the k-space center provided faster and more motion-robust CEST imaging than Cartesian trajectories. B0 inhomogeneities were estimated using the phase difference between two images from two halves of the rosette lobe and corrected subsequently.
Results: Rosette trajectories significantly reduced the CEST imaging time. No extra scans were needed for B0 correction due to the inherent B0 mapping capability.
Impact: Fast, motion-robust, and inherent B0-corrected CEST imaging with rosette trajectories can help improve patient comfort and compliance. The work is expected to significantly accelerate the translation of CEST-MRI into a robust clinically viable approach.
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