Keywords: Pulse Sequence Design, Spectroscopy, UTE, Rosette Spectroscopic Imaging, 4D JRESI
Motivation: Two-dimensional spectrum resolves information-coupled metabolites along an additional spectral dimension. However, acquisition after adding the 2nd spectral encoding can increase the total acquisition time significantly.
Goal(s): To achieve clinically feasible runtimes for J-resolved Spectroscopic Imaging (JRESI) using Ultra-Short Echo-Time (UTE) based sequence implementation.
Approach: Implement a UTE based 4D JRESI sequence with rosette readout, which would enable shorter repetition times and use of higher undersampling factors.
Results: This study demonstrated in-vivo 4D UTE-ROSE-JRESI in less than 10 minutes as compared to a semi-laser sequence with a TR of 1.5 seconds which will take 17 minutes for the same sequence.
Impact: With higher incoherence level of sampling patterns rosette based spectroscopic imaging sequence showed the potential for highly accelerated acquisitions. Using UTE based rosette 4D J-resolved Spectroscopic Imaging sequence allowed further reduction in scan time with the help of shorter TR.
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