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Abstract #1146

Ultra-Short Echo-Time Based Accelerated Four-Dimensional Rosette J-resolved Spectroscopic Imaging (4D UTE-ROS-JRESI): A pilot study

Ajin Joy1, Uzay Emir2, Paul Macey3, and M. Albert Thomas1
1Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, 2College of Health and Human Sciences, Purdue University, West Lafayette, IN, United States, 3School of Nursing, University of California, Los Angeles, Los Angeles, CA, United States

Synopsis

Keywords: Pulse Sequence Design, Spectroscopy, UTE, Rosette Spectroscopic Imaging, 4D JRESI

Motivation: Two-dimensional spectrum resolves information-coupled metabolites along an additional spectral dimension. However, acquisition after adding the 2nd spectral encoding can increase the total acquisition time significantly.

Goal(s): To achieve clinically feasible runtimes for J-resolved Spectroscopic Imaging (JRESI) using Ultra-Short Echo-Time (UTE) based sequence implementation.

Approach: Implement a UTE based 4D JRESI sequence with rosette readout, which would enable shorter repetition times and use of higher undersampling factors.

Results: This study demonstrated in-vivo 4D UTE-ROSE-JRESI in less than 10 minutes as compared to a semi-laser sequence with a TR of 1.5 seconds which will take 17 minutes for the same sequence.

Impact: With higher incoherence level of sampling patterns rosette based spectroscopic imaging sequence showed the potential for highly accelerated acquisitions. Using UTE based rosette 4D J-resolved Spectroscopic Imaging sequence allowed further reduction in scan time with the help of shorter TR.

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