Keywords: Thermometry/Thermotherapy, Thermometry
Motivation: Proton resonance frequency (PRF)-shift thermometry is the current standard for MR-temperature monitoring in interventional procedures. However, the long TE required for phase contrast induces signal dropout and increases sensitivity to metal and motion artifacts.
Goal(s): Use quadratic RF phase (qRF) MR fingerprinting to image off-resonance frequency for thermometry at a real time frame rate.
Approach: Because PRF change is much more sensitive to temperature change in aqueous tissue than T1/T2, we propose a “lightweight” constant low-flip-angle MRF sequence optimized for 3s or less frame rate to measure temperature from the PRF shift.
Results: We implemented qRF-MRF thermometry with high spatiotemporal resolution.
Impact: A thermometry method with high temporal resolution that does not suffer from signal dropout at high temperatures can enable more accurate temperature monitoring for MR-guided interventional procedures. Additionally, it has potential to be more robust to motion artifacts.
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