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Abstract #1384

Cardiac QSM for the Detection of Intra-Myocardial Haemorrhage: an Initial Experience

Andrew Tyler1, Matthew Li Kam Wa1, Anmol Kaushal1, Filippo Bosio1, Pier Giorgio Masci1, and Sébastien Roujol1
1Biomedical Engineering and Imaging Science, King's College London, London, United Kingdom

Synopsis

Keywords: Myocardium, Susceptibility

Motivation: T2*-contrast is not-specific to iron in the heart, with edema having a competing and contradictory effect to iron. Quantitative susceptibility mapping (QSM) may improve identification of intra-myocardial haemorrhage (IMH), through greater specificity to iron.

Goal(s): To present our initial experience of using QSM for the assessment of IMH.

Approach: 10 patients were scanned with QSM, 5 without myocardial infarcts to perform AHA-segmental analysis and 5 with scar to demonstrate the identification of IMH with QSM.

Results: The mean AHA-segment susceptibility was 0.00±0.02ppm and precision 0.05±0.03ppm in the non-infarct-group. Four of the patients with scar had IMH, which was successfully identified with QSM.

Impact: Cardiac quantitative susceptibility mapping successfully visualized intra-myocardial haemorrhage in four patients, and found no haemorrhage in one further patient, in agreement with the gold standard T2/T2* techniques.

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