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Abstract #1402

Learning to synthesize MR contrasts using a self-supervised constrained contrastive learning approach

Lavanya Umapathy1,2, Li Feng1,2, and Daniel K Sodickson1,2
1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States

Synopsis

Keywords: Analysis/Processing, Machine Learning/Artificial Intelligence

Motivation: Although deep learning frameworks have been widely used in all aspects of the MR imaging pipeline, the effect of learning tissue-specific information from MR images in improving model performance needs to be understood.

Goal(s): We demonstrate the utility of a self-supervised contrastive learning framework that uses multi-contrast information to improve synthesis of T1w and T2w images.

Approach: A deep learning model is pretrained to learn T1 and T2 information from a set of multi-parametric MR images.

Results: A contrast synthesis framework was developed using few examples of contrast mapping. Embedding relevant contrast information during pretraining synthesized images with improved MSE, SSIM, and PSNR.

Impact: Multi-contrast information can be leveraged by self-supervised deep learning models to understand underlying tissue characteristics and synthesize new MR contrast-weighted images. This demonstrates the wider applicability of embedding tissue-specific information in improving different aspects of the MR imaging pipeline.

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