Abstract #1634

Comparison of lesion detection performance between 3D high-resolution isotropic MRI using MIXTURE and conventional 2D-TSE in knee joints

Takayuki SAKAI^1,2, Masami Yoneyama³, Shuo Zhang⁴, Hajime Yokota⁵, Kaoru Kitsukawa⁶, Daichi Murayama¹, Shigehiro Ochi¹, and Tosiaki Miyati²

¹Radiology, Eastern Chiba Medical Center, Chiba, Japan, ²Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Ishikawa, Japan, ³Philips Japan, Tokyo, Japan, ⁴Philips Healthcare, Hamburg, Germany, ⁵Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan, ⁶Radiology, Chiba University Hospital Comprehensive Radiology Center, Chiba, Japan

Synopsis

Keywords: Cartilage, MSK

Motivation: Cartilage degeneration can be evaluated non-invasively by quantitative T2 mapping MRI. However, clinical knee joint MRI requires multiple contrasts to diagnose various diseases, and T2 mapping for quantitative evaluation must be additionally performed.

Goal(s): To evaluate the lesion detection performance between 2D-TSE and 3D MIXTURE in clinical knee MRI.

Approach: MIXTURE is a 3D TSE that can set arbitrary echo times using the T2 preparation pulses, and enables several image contrasts and T2 mapping by acquiring at least two echo time images.

Results: With regard to the lesion depiction, 3D MIXTURE and conventional 2D TSE were considered comparable with equivalent diagnostic confidence.

Impact: MIXTURE can acquire morphological and quantitative images in a single scan. We evaluated the diagnostic accuracy of the morphological images. We will clarify the diagnostic accuracy of MIXTURE by comparing it with the conventional 2D-TSE method for knee joints.

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