Keywords: Myocardium, Myocardium, pulmonary hypertension; mechanical dyssynchrony;
Motivation: The ability of layer-specific intraventricular mechanical dyssynchrony (M-dys) to predict prognosis in pulmonary arterial hypertension (PAH) has not been investigated.
Goal(s): To illustrate the existence and prognostic values of layer-specific intraventricular M-dys and its associations with electronical dyssynchrony in PAH.
Approach: The biventricular volumetric and layer-specific intraventricular M-dys were analyzed by calculating strain and strain rate based on cine cardiac magnetic resonance images.
Results: The layer-specific intraventricular M-dys had varying impacts on biventricular functions in PAH.
Impact: This study was novel in reporting that the layer-specific intraventricular M-dys had various distribution patterns in both ventricles in patients with PAH.
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